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Index > Protein center > CMPK1(Gene name) > Human
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  • CMPK1 (Gene name),
  • UMP-CMP kinase (Protein name ),  KCY_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CMPK1(CMK;CMPK;UCK;UMK;UMPK);
    Protein name:
    UMP-CMP kinase;
    Alternative:
    2.7.4.6;Cytidylate kinase);Cytidine monophosphate kinase(CK);Uridine monophosphate kinase;Deoxycytidylate kinase(UMP/CMP kinase);Uridine monophosphate/cytidine monophosphate kinase(UMP/CMP kinase;UMP/CMPK);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.
    Subcellular Location:
    Nucleus Cytoplasm Mainly nuclear.
    Protein Attributes:
    Sequence length:
    196
    Sequence:
    50:
    MKPLVVFVLG | GPGAGKGTQC | ARIVEKYGYT | HLSAGELLRD | ERKNPDSQYG | 
    100:
    ELIEKYIKEG | KIVPVEITIS | LLKREMDQTM | AANAQKNKFL | IDGFPRNQDN | 
    150:
    LQGWNKTMDG | KADVSFVLFF | DCNNEICIER | CLERGKSSGR | SDDNRESLEK | 
    196:
    RIQTYLQSTK | PIIDLYEEMG | KVKKIDASKS | VDEVFDEVVQ | IFDKEG
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    KEGG:
    UniGene:
    SMR:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human UMP-CMP kinase
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    E14030h
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    ELISA Kit for Human UMP-CMP kinase
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    E14030m
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    ELISA Kit for Human UMP-CMP kinase
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    E14030r
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    ELISA Kit for Human UMP-CMP kinase
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    E14030c
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    ELISA Kit for Human UMP-CMP kinase
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    E14030p
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    ELISA Kit for Human UMP-CMP kinase
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    E14030b
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    96T
    CLIA Kit for Human UMP-CMP kinase
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    U14030m
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    CLIA Kit for Human UMP-CMP kinase
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    U14030h
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    CLIA Kit for Human UMP-CMP kinase
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    U14030b
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    CLIA Kit for Human UMP-CMP kinase
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    U14030p
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    CLIA Kit for Human UMP-CMP kinase
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    CLIA Kit for Human UMP-CMP kinase
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    Packing:
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    Polyclonal Antibody for Human UMP-CMP kinase
    Polyclonal Antibody for Human UMP-CMP kinase
    Polyclonal Antibody for Human UMP-CMP kinase
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    P14030Rb-h
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    Packing:
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    Polyclonal Antibody for Human UMP-CMP kinase
    Polyclonal Antibody for Human UMP-CMP kinase
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    P14030Rb-m
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    Polyclonal Antibody for Human UMP-CMP kinase
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    P14030Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human UMP-CMP kinase
    Monoclonal Antibody for Human UMP-CMP kinase
    Monoclonal Antibody for Human UMP-CMP kinase
    Monoclonal Antibody for Human UMP-CMP kinase
    Monoclonal Antibody for Human UMP-CMP kinase
    Monoclonal Antibody for Human UMP-CMP kinase
    Protein for Human UMP-CMP kinase
    Protein for Human UMP-CMP kinase
    Protein for Human UMP-CMP kinase
    Protein for Human UMP-CMP kinase
    Protein for Human UMP-CMP kinase
    Protein for Human UMP-CMP kinase

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    References
    1. 1.
      "Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme."
      Van Rompay A.R. , Johansson M. , Karlsson A.
      Mol. Pharmacol.56:562-569(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;FUNCTION
    2. 2.
      "Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region."
      Pearman A.T. , Castro-Faria-Neto H.C. , McIntyre T.M. , Prescott S.M. , Stafforini D.M.
      Life Sci.69:2361-2370(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;CHROMOSOMAL LOCATION;IDENTIFICATION OF START CODON
      tissue: Macrophage.
    3. 3.
      "Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates."
      Liou J.-Y. , Dutschman G.E. , Lam W. , Jiang Z. , Cheng Y.-C.
      Cancer Res.62:1624-1631(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;SUBCELLULAR LOCATION
    4. 4.
      "Human UMP-CMP kinase gene."
      Song H. , Peng Y. , Dai M. , Huang Q. , Mao Y. , Zhang Q. , Mao M. , Fu G. , Luo M. , Chen J. , Hu R.
      Submitted (1998-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Pituitary.
    5. 5.
      "Cloning and characterization of a new human cDNA homologous to pig UMP-CMP kinase mRNA."
      Fan Y.X. , Yu L. , Dai F.Y. , Zhou Y. , Huang J. , Zhao S.Y.
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Hypothalamus.
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    8. 8.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Small intestine.
    9. 9.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    10. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Muscle.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-29
      tissue: Liver.
    12. 12.
      "Human liver protein map: a reference database established by microsequencing and gel comparison."
      Hochstrasser D.F. , Frutiger S. , Paquet N. , Bairoch A. , Ravier F. , Pasquali C. , Sanchez J.-C. , Tissot J.-D. , Bjellqvist B. , Vargas R. , Appel R.D. , Hughes G.J.
      Electrophoresis13:992-1001(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-10
      tissue: Liver.
    13. 13.
      Bienvenut W.V. , Bilsland A.E. , Keith W.N.
      Submitted (2010-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-16; 62-73; 89-106; 152-171 AND 180-196;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Colon carcinoma.
    14. 14.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-55;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      "The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase."
      Amiri M. , Conserva F. , Panayiotou C. , Karlsson A. , Solaroli N.
      Int. J. Biochem. Cell Biol.45:925-931(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY
    17. 17.
      "Substrate-induced conformational changes in human UMP/CMP kinase."
      Segura-Pena D. , Sekulic N. , Ort S. , Konrad M. , Lavie A.
      J. Biol. Chem.279:33882-33889(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS)
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